MuGam is a homologue of eukaryotic proteins Ku70/Ku80, which are involved in recognizing double-strand DNA prior to repair, as well as DNA transposition. In Haemophilus influenzae, Gam (HiGam) inhibits digestion of Mu phage DNA by nucleases (d’Adda di Fagagna, Weller, Doherty, et al., 2003).
The aim of this report is to characterise HiGam by processing the data obtained from the following experiments:
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d’Adda di Fagagna, F., G. R. Weller, A. J. Doherty, et al. (2003). “The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku”. En. In: EMBO reports 4.1, pp. 47-52.